Repeated exposure to cocaine during adolescence enhances the rewarding threshold for cocaineconditioned place preference in adulthood

L Caffino, F Moro, F Mottarlini, G Targa… - Addiction …, 2021 - Wiley Online Library
… to a rewarding dose of cocaine (10 mg/kg) elevating the … induced cocaine seeking in rats
after extended withdrawal from … If this holds true, our findings are in agreement with a previous

Assessment of cocaine-induced behavioral sensitization and conditioned place preference in mice

LN Smith, RD Penrod, M Taniguchi… - JoVE (Journal of …, 2016 - jove.com
… In rodents, reward experience and contextual associations … 1) pre-test preference scores
for the (eventual) cocaine-paired … - and post-tests, increases in the cocaine-paired side can be …

Initial rewarding effects of cocaine and amphetamine assessed in a day using the single‐exposure place preference protocol

AH Runegaard, KL Jensen… - European Journal of …, 2019 - Wiley Online Library
… DA signalling prior to drug exposure affects either reward-… The most commonly used models
are the conditioned place preference (… , is targeting dopaminergic neurons and increases

Cocaine-induced behavioral sensitization is greater in adolescent than in adult mice and heightens cocaine-induced conditioned place preference in adolescents

R Camarini, LB Hoffmann, A Suarez, M Rae… - Pharmacology …, 2019 - Elsevier
… of drug reward, such as conditioned place preference (CPP), has … showed an earlier onset
of cocaine-induced increases of … size that surpassed the threshold for being considered large. …

… -paired cues in a rat gambling task increases sensitivity to cocaine self-administration and suppresses dopamine efflux in nucleus accumbens: support for the reward …

JMN Ferland, TJ Hynes, CD Hounjet… - Journal of …, 2019 - Soc Neuroscience
… Animals underwent consecutive daily rGT and cocaine self-… In Experiment 2, locomotor
testing was first performed before … , but levers would remain extended and responses monitored. …

The association between risky decision making and cocaine conditioned place preference is moderated by sex

JR Yates, MJ Horchar, JL Kappesser… - Drug and alcohol …, 2021 - Elsevier
… the pre-test was the one that was paired with cocaine during the … , the relationship between
reward thresholds and cocaine self-… differences in cocaine-induced increases in locomotor …

Less is more: prolonged intermittent access cocaine self-administration produces incentive-sensitization and addiction-like behavior

AB Kawa, BS Bentzley, TE Robinson - Psychopharmacology, 2016 - Springer
… to attribute incentive salience to reward cues (sign-trackers [… were never given the day directly
before a probe test off. The … , or how readily demand decreases as price increases; (4) an …

Synaptic depotentiation and mGluR5 activity in the nucleus accumbens drive cocaine-primed reinstatement of place preference

MA Benneyworth, MC Hearing, AJ Asp… - Journal of …, 2019 - Soc Neuroscience
Cocaine-conditioned place preference behavior and ex vivo … reward-seeking driven by
conditioned contextual associations. … priming injection before reinstatement testing (Coc-Coc), a …

Individual differences in dopamine uptake in the dorsomedial striatum prior to cocaine exposure predict motivation for cocaine in male rats

JK Shaw, I Pamela Alonso, SI Lewandowski… - …, 2021 - nature.com
Cocaine conditioned place preference (CPP) experiments … the ratio of effort to reward to
measure cocaine-seeking, we … The observed increases in pre-synaptic sensitivity to cocaine

Individual differences in cocaine-induced conditioned place preference in male rats: Behavioral and transcriptomic evidence

LA Atehortua Martinez, E Curis… - Journal of …, 2022 - journals.sagepub.com
… of the rewarding effects of cocaine in the conditioned place … during the pre and post
conditioning test. After each series of … Our results extend this regulation to other IEGs only in the …